Oloa
2,4-Diamino-6-hydroxypyrimidine
Hydroxypyrimidine Meatotino Vailaau
| Liu liusuavai | 285-286 °C (tes.) (malamalama) |
| Fa'apuna | 234.22°C (fa'atatau fa'atatau) |
| mafiafia | 1.3659 (fa'atatau fa'atatau) |
| fa'asino fa'asino | 1.7990 (fa'atatau) |
| vevela vevela. | Taofi i se nofoaga pogisa, Inert atemosifia, potu vevela |
| solubility | DMSO (La'iti), Methanol (La'u) |
| pka | 10.61±0.50(Vavaloa) |
| fomu | Pa'u tioata lelei |
| lanu | Pa'epa'e i le kulimi |
| Ma'ale'ale | Ma'ale'ale |
| Merck | 14,2981 |
| BRN | 125006 |
| InChIKey | SWELIMKTDYHAOY-UHFFFAOYSA-N |
| CAS Fa'amaumauga Fa'amaumauga | 56-06-4(Fa'amatalaga Fa'amaumauga a le CAS) |
| NIST Chemistry Reference | 4(1H)-pyrimidinone, 2,6-diamino-(56-06-4) |
| Faiga Fa'atusitala a le EPA | 2,6-Diamino-4(1H)-pyrimidinone (56-06-4) |
Hydroxypyrimidine Faʻamatalaga o oloa
2,4-Diamino-6-hydroxypyrimidine o se vailaʻau vailaʻau faʻatasi ai ma le fua mole mole C4H6N4O.O se fa'alapotopotoga fa'aola o le aiga pyrimidine.O le tuufaatasiga o loʻo i ai se fausaga mama pyrimidine, e lua vaega amino (NH2) e fesoʻotaʻi i le 2-tulaga ma le 4-tulaga, ma le hydroxyl group (OH) e fesoʻotaʻi i le 6-tulaga.E mafai ona fa'aalia le fausaga o vaila'au: Amonia ||H--C--C--C--N--C--C--NH2 ||oh 2,4-Diamino-6-hydroxypyrimidine o loʻo i ai faʻaoga eseese i le falemaʻi vailaʻau.O se mea taua tele i le tuʻufaʻatasia o le tele o vailaʻau, e aofia ai vailaʻau antiviral ma antitumor.E fa'aaogaina fo'i e gaosia ai le tele o analog nucleotide fa'aaogaina i su'esu'ega vaila'au.
I le faʻaopoopoga i vailaʻau faʻapitoa, 2,4-diamino-6-hydroxypyrimidine o loʻo faʻaaogaina foi e fai ma mea e faʻaaogaina i agrochemicals.O se vaega autu i le tuʻufaʻatasia o faʻatonuga o le tuputupu aʻe o laau ma fungicides.E taua tele le mulimulitaʻia o se faʻatonuga saogalemu pe a faʻaaogaina le 2,4-diamino-6-hydroxypyrimidine.Talu ai o lo'o fa'avasegaina ose vaila'au fa'aaono, e tatau ona taulimaina ma le fa'aeteete ma ia lava mea e puipuia ai le tagata lava ia e tatau ona ofuina e aloese ai mai le fa'afeso'ota'i sa'o.
I le aotelega, 2,4-diamino-6-hydroxypyrimidine o se faʻalapotopotoga faʻapitoa ma faʻaoga i vailaʻau ma faʻatoʻaga.O lona fausaga vailaʻau e faʻaaogaina e avea o se vaeluagalemu i le tuʻufaʻatasia o vailaʻau ma faʻatonuga o le tuputupu aʻe o laau.
Fa'amatalaga Saogalemu
| Laiti o lamatiaga | Xi |
| Fa'amatalaga Tulaga lamatia | 36/37/38 |
| Fa'amatalaga Saogalemu | 22-24/25-36-26 |
| WGK Siamani | 3 |
| Mata'utia Fa'amatalaga | Fa'aitaita |
| TSCA | Ioe |
| HS Code | 29335995 |
Hydroxypyrimidine Fa'aaogāina ma Fa'asologa
| Fa'amatalaga | 2,4-Diamino-6-hydroxypyrimidine (DAHP) o se filifili, faʻamaonia faʻapitoa ole GTP cyclohydrolase I, o le fua faʻatapulaʻa laasaga mo de novo pterin synthesis.I sela HUVEC, o le IC50mo le taofiofia o le BH4biosynthesis e tusa ma le 0.3 mM.E mafai ona fa'aoga le DAHP e poloka lelei ai le NO gaosiga i le tele o ituaiga sela. |
| Meatotino tau vailaau | Pa'epa'e Malosi |
| Fa'aoga | 2,4-Diamino-6-hydroxypyrimidine (DAHP) o se filifili, faʻamaonia faʻapitoa ole GTP cyclohydrolase I, o le fua faʻatapulaʻa laasaga mo de novo pterin synthesis.I sela HUVEC, o le IC50 mo le taofia o le BH4 biosynthesis e tusa ma le 0.3 mM.E mafai ona fa'aoga le DAHP e poloka lelei ai le NO gaosiga i le tele o ituaiga sela.[Cayman Chemical] |
| Fa'aoga | O loʻo tu i le amataga o le enzyme-catalyzed cascade lea e amata i lenei carbohydrate e fitu-carbon ma faʻaiʻu i le amino acids phenylalanine, tyrosine, ma tryptophan. |
| Fa'aoga | 2,4-Diamino-6-hydroxypyrimidine (cas # 56-06-4) o se faʻapipiʻi aoga i le faʻaogaina o meaola. |
| Auala Fa'amamāina | E toe fa'asalaina mai le H2O.[Beilstein 25 III/IV 3642.] |
